Wuzhizhou Island (Chinese: 蜈支洲岛; pinyin: Wúzhīzhōu dǎo) is located off the coast of Hainan Province, China.

This 1.48 square kilometre island is situated within Haitang Bay, approximately 30 kilometres northeast of Sanya, between Nanwan Monkey Island to the north, and Yalong Bay to the south.

The Taoist priest Wu Huacun of the Qing dynasty built a house on the island after arriving in search of a place to create the "elixir of life".

The waters surrounding the island contain numerous species such as sea cucumbers, urchins, and tropical fish.

The "sea ranch" planned 18,000 cubic meters of artificial reefs over an area of approximately 66.6 hectares.