Wycombe (/ˈwɪkəm/) is a constituency in Buckinghamshire represented in the House of Commons of the UK Parliament since 2024 by Labour's Emma Reynolds.

The constituency shares similar borders with Wycombe local government district, although it covers a slightly smaller area.

The surrounding villages, which account for just under half of the electorate, are some of the most wealthy areas in the country, with extremely low unemployment, high incomes and favour the Conservatives.

1945–1950 The House of Commons (Redistribution of Seats) Act 1944 set up Boundaries Commissions to carry out periodic reviews of the distribution of parliamentary constituencies.

1974–1983 Northern parts of the Rural District of Wycombe, including Princes Risborough, but excluding Hughenden, were transferred back to Aylesbury.

In April 2020, the District of Wycombe, together with those of Aylesbury, Chiltern and South Bucks were merged into the new unitary authority of Buckinghamshire Council.