Wysox is an unincorporated community in Bradford County, Pennsylvania, United States.

[2][3] Wysox had a population of 1,721 and 800 housing units as of the 2010 census.

Its name comes from a Native American word meaning "canoe harbor."

[7] Wysox's Board of Supervisors currently consists of Chairman William Them, Evan R. Barnes, and Thomas C. Thompson III.

[9] Wysox is in the Towanda Area School District.