The initial staff consisted of Madrox's best friend and special enforcer, Guido Carosella (Strong Guy) and former teammate Rahne Sinclair (Wolfsbane).

Following the House of M, Madrox's newfound wealth from winning a Who Wants to Be a Millionaire-style game show allowed him to recruit several of his former colleagues of the Paris branch of the now defunct X-Corporation.

Singularity Investigations was representing Jack Vaughn with Tryp, Junior (in other words, the youngest version) as the defense counsel.

[11] When a former Singularity employee came to X-Factor Investigations and related that Tryp is attempting to recreate the Legacy Virus, the plague that killed several mutants, including, briefly, Madrox himself,[6]Strong Guy is sent to drive the man to safety.

According to the oldest version of Tryp (ancient), all of Singularity Investigations' efforts to create the Legacy Virus have been to prevent a possible future in which X-Factor manages to undo the Decimation, but as a result, humanity is wiped out by the re-powered mutants in a bloody conflict.

[12] After the destruction of Singularity Investigations, the present form of Damian Tryp (the elder/ancient) reveals to Layla that her very existence had foiled his plans — she is a force of chaos like he is.

Following her encounter with Tryp, Layla appears genuinely shocked for the first time: the glass of milk she is pouring overflows, spilling onto the floor.

All but Marrow and Callisto were repowered by Quicksilver and Rictor—a process that resulted in the death of Elijah Cross, their leader, and Abyss, Fatale and Reaper fleeing into the brimstone dimension to fate unknown.

[13] During the "Messiah Complex" storyline, Madrox, Rictor, and an accompanying Layla Miller are alerted to the Xavier Mansion by Emma Frost during the mutant baby conflict.

[15] Meanwhile, Mutant Town is under the clutches of Silver Age X-Men villain Arcade with Rictor as his prisoner; Valerie Cooper returns as a supporting character and X-Factor relocates to Detroit, Michigan.

[volume & issue needed] To address the absence of Layla Miller and Rahne Sinclair, and to add new character dynamics to the team, writer Peter David added new cast members to the book, Longshot and Darwin.

Darwin's father hires X-Factor to find his son, supposedly because he feels bad for walking out on him and his mother when he was younger.

[23] Jamie is transported to the future in the midst of the Summers Rebellion, where mutants rise up against Sentinel and human oppressors, which is led by Ruby Summers, the daughter of Cyclops and Emma Frost with her fathers' optic blasts and Emma's organic mineral body, Layla, and a cyborg Cyclops, whose predicament is Jamie's fault.

The group visit an aging, senile Doctor Doom, who says Layla told him in the past that he'd have to instruct Jamie and her on something in the future, and it is now.

[volume & issue needed] In the present, X-Factor and new members Longshot and Darwin are battling Cortex, an agent of the Summers Rebellion era government.

Cortex briefly controls Shatterstar and M, using them to respectively make assassination attempts on Reverend John Maddox and an X-Factor client.

In their first mission, the team is approached by Valeria and Franklin Richards, who ask for X-Factor's help to locate their mother, The Invisible Woman, who has mysteriously vanished.

Longshot identifies from clues left on the Fantasticar that Sue was kidnapped to Latveria and in a vision sees Layla Miller allied with Doctor Doom.

[volume & issue needed] During the "Second Coming" storyline, Bolivar Trask, after being given the mission to kill all members of the X-Factor team, assigns Absorbing Man and Bastion to the task.

Because of her Catholic beliefs, she attacks Shatterstar in her wolf form and pushes him to the ground from the window for "turning" Rictor gay, but they are interrupted by Longshot.

The team sets out to Las Vegas to rescue him by using Longshot's power to win at casino for four months to gain attention.

[27] While in the heat of a battle to rescue J. Jonah Jameson, Strong Guy was shot and killed, but Layla revived him at the cost of his soul.

The spirit of Doc Strange was able to send Jamie back to his reality, but complications drew Vanora, Deathlok and Dormammu with him.

It was later reviewed that they are the Hell Lords who is awaken by Guido's resurrection by Layla and the birth of Rahne's baby son, Tier.

Pip was seemingly killed by the Hell Lords in an effort to protect the team, and later possess M's body in order to escape his death.

Polaris found herself in NY without any member of her team, got drunk and attempted a suicide-by-cop and got thrown in jail, where she made a deal with a mysterious figure (later revealed to be Harrison Snow).

Upon returning to where the X-Factor building once stand, Jamie, frustrated over the situation and concluded that the world is for "other people to save", sold the team to Harrison Snow - CEO and president of Serval Industry, and retired to his family farm with Layla - his pregnant wife.

[36][37] Peter David said this in an interview later: "I’m appreciative of Marvel Comics allowing me so much latitude in X-Factor, particularly Joe Quesada's unequivocal public support when Rictor and Shatterstar first liplocked.

I note that the award only names me, and I think that’s shortsighted, because there’s been a host of artists and editors along the way who have done a terrific job to bring the stories to the public.

And ultimately I look forward to the day when this award is utterly unnecessary because the positive portrayal of LGBTs is simply so commonplace that it’s no longer newsworthy.