The station is owned by Grupo Radiofónico Zer and broadcasts a Spanish-language adult hits format known as Lupe 100.1.
The station was sold to XEGUZ, S.A. de C.V. in 1987; the call sign was changed to XEMZA around that time period.
The FM transmitter later moved across the state line to Cerro del Toro as part of a class upgrade.
In October 2022, the Federal Telecommunications Institute (IFT) approved XHMZA-FM to change frequencies from 89.7 to 100.1 MHz, which occurred the following month.
The change was intended to resolve an interference issue caused by intermodulation of XHMZA-FM and Manzanillo's XHMAC-FM 95.3 to frequencies in the 162 MHz range used by the Comisión Federal de Electricidad.