Xigu District (Chinese: 西固区; pinyin: Xīgù Qū) is one of 5 districts of the prefecture-level city of Lanzhou, the capital of Gansu Province, Northwest China.

Until 1952, Xigu was part of Gaolan County as a township and in 1953 it was established as the fifth district level division of Lanzhou.

[1] During this period, as part of China's first five-year plan, the petrochemical industry was developed in the area.

[2] Xigu is divided in 7 subdistricts 5 towns and 1 township:[3] Xigu District is highly industrialized, and most of Lanzhou's heavy industry is located in the district, including PetroChina's Lanzhou Petrochemical complex,[4] an aluminium smelting plant, power plants, and textile industry.

[5] It was also the site of a nuclear enrichment factory, completed in 1958, which provided the material for China's first atomic bomb.