[2][3] Xin Lu completed her undergraduate education in Biochemistry at Sichuan University in 1982 and her master's degree in Cell and Molecular Biology at the Cancer Institute, Peking Union Medical College & Chinese Academy of Medical Sciences in 1985.

She moved to University College London (UCL)[4] to complete her PhD studies supervised by Birgit Lane,[5] and published her thesis A study of intermediate filament formation using retrovirus-mediated gene transfer in 1991.

[6] In 1993, after a short postdoc with David Lane at Dundee University, she joined the Ludwig Institute for Cancer Research (LICR), which was based at St Mary's Hospital, Imperial College London and set up her own research group.

"Differential induction of transcriptionally active p53 following UV or lonizing radiation: Defects in chromosome instability syndromes?".

Hsieh, Jung-Kuang; Chan, Florence S.G; O’Connor, Daniel J; Mittnacht, Sibylle; Zhong, Shan; Lu, Xin (1999).

Samuels-Lev, Yardena; O'Connor, Daniel J.; Bergamaschi, Daniele; Trigiante, Giuseppe; Hsieh, Jung-Kuang; Zhong, Shan; Campargue, Isabelle; Naumovski, Louie; Crook, Tim (2001).

"A Code for RanGDP Binding in Ankyrin Repeats Defines a Nuclear Import Pathway".

Bergamaschi, Daniele; Samuels, Yardena; O'Neil, Nigel J.; Trigiante, Giuseppe; Crook, Tim; Hsieh, Jung-Kuang; O'Connor, Daniel J.; Zhong, Shan; Campargue, Isabelle (2003).

Notari, Mario; Hu, Ying; Sutendra, Gopinath; Dedeić, Zinaida; Lu, Min; Dupays, Laurent; Yavari, Arash; Carr, Carolyn A.; Zhong, Shan (2015-03-03).

"iASPP, a previously unidentified regulator of desmosomes, prevents arrhythmogenic right ventricular cardiomyopathy (ARVC)-induced sudden death".

Wang, Yihua; Bu, Fangfang; Royer, Christophe; Serres, Sébastien; Larkin, James R.; Soto, Manuel Sarmiento; Sibson, Nicola R.; Salter, Victoria; Fritzsche, Florian (2014).

Turnquist, Casmir; Wang, Yihua; Severson, David T.; Zhong, Shan; Sun, Bin; Ma, Jingyi; Constantinescu, Stefan N.; Ansorge, Olaf; Stolp, Helen B.

"STAT1-induced ASPP2 transcription identifies a link between neuroinflammation, cell polarity, and tumor suppression".

Lu, Min; Breyssens, Hilde; Salter, Victoria; Zhong, Shan; Hu, Ying; Baer, Caroline; Ratnayaka, Indrika; Sullivan, Alex; Brown, Nicholas R. (2013).

"Restoring p53 Function in Human Melanoma Cells by Inhibiting MDM2 and Cyclin B1/CDK1-Phosphorylated Nuclear iASPP".

Notari, Mario; Hu, Ying; Koch, Sofia; Lu, Min; Ratnayaka, Indrika; Zhong, Shan; Baer, Caroline; Pagotto, Anna; Goldin, Robert (2011-10-04).

"Inhibitor of apoptosis-stimulating protein of p53 (iASPP) prevents senescence and is required for epithelial stratification".

Slee, Elizabeth A.; Benassi, Barbara; Goldin, Robert; Zhong, Shan; Ratnayaka, Indrika; Blandino, Giovanni; Lu, Xin (2010-11-09).