Aimed towards teenagers, the block consists of six half-hour shows focusing on the STEM fields of science, technology, engineering, and mathematics.

On December 17, 2013, Steve Rotfeld Productions announced that it would launch a two-hour syndicated block of live-action educational programs under the working title Xploration Nation, with Fox Television Stations and Tribune Broadcasting initially set to carry the block across their respective Fox owned-and-operated and affiliated stations.

The block, aimed towards teenagers between 13 and 16 years of age, features programs focused on the STEM fields – such as marine biology, astronomy, and animal science.

[4] On Fox owned and operated stations, Xploration Station replaced Weekend Marketplace, a two-hour block of infomercials first introduced in January 2009 following the discontinuation of 4Kids TV due to conflicts between Fox and the block's programmer 4Kids Entertainment.

[7] The block was made available worldwide with the pick up of non-US distribution by Boat Rocker Rights in February 2016.