In 1921–22, together with Shelbourne, Bohemians, St James's Gate, Jacobs, Olympia, Dublin United and Frankfort, YMCA were founder members of the League of Ireland.
Like the other seven founding members, YMCA had spent the 1920–21 season playing in the Leinster Senior League.
YMCA eventually finished in 8th and last place after failing to win a single game.
[2] In the 1921–22 FAI Cup YMCA lost 4–3 at home to Athlone Town in the first round.
[3] Together with Frankfort, Rathmines Athletic and Reds United, YMCA are one of only four clubs to have played just one season in the top level of the League of Ireland.