It has exceptionally complete performer expression features, such as a layered keyboard that was both velocity-sensitive (like a piano's) and pressure-sensitive ("after-touch") but unlike most modern keyboards the aftertouch could be applied to individual voices rather than in common, and a ribbon controller allowing for polyphonic pitch-bends and glissandos.

At the 2014 NAMM Show, Studio Electronics premiered the Boomstar SE80 synthesizer which includes a cloned filter section of the CS-80.

Black Corporation's Deckard's Dream (2017) and upcoming Deckard's Dream MK2 (autumn 2024) are rackmount synthesizer with CS-80 inspired architectures and features which support polyphonic aftertouch using compatible third party external keyboards.

It needs a lot of practice if you want to be able to play it properly, but that's because it's the only synthesizer I could describe as being a real instrument, mainly because of the keyboard — the way it's built and what you can do with it.

"[7] The CS-80's features can be heard on the Blade Runner soundtrack by Vangelis, in which CS-80 is featured prominently, as well as the composer's soundtrack for the film Chariots of Fire, and the bassline of Peter Howell's interpretation of the 1980 theme tune to the BBC science fiction show Doctor Who.