It is located on Soho's Wardour Street, and the majority of the building has Grade II Listed status.

Musical instruments offered include pianos (acoustic and electric), guitars (acoustic, electric, basses), drums & percussion, brass (horns, cornets, trombones, trumpets, tubas), woodwinds (oboes, bassoons, clarinets, flutes, saxophones), bowed (cellos, violas, violins), and accessories.

Kemble & Company ran a joint venture with Yamaha in Japan (then called the Nippon Gakki company) - trading as Yamaha-Kemble, the business successfully brought Yamaha organs, digital pianos and later guitars, orchestral instruments and professional music equipment into the UK where they acted as exclusive distributor.

The Chappell of Bond Street stores (now including a second store in Yamaha Kemble's home town of Milton Keynes) acted as major retail outlets for the imported Yamaha products, as well as selling Chappell pianos and sheet music (now bought in from external suppliers).

In September 2005, the Milton Keynes branch of Chappell of Bond Street closed with sources citing the end of the original 25-year lease and the spiralling costs of shopping centre rental rates as the cause.

Whilst the 'new' store was praised for its spacious and welcoming atmosphere, some long-term customers were saddened to see the shrinkage of the sheet music department (which, in its heyday, occupied the entire basement floor).

The store comprises four floors, three of which serve as retail areas: The Piano Hall has regularly been used as an intimate concert venue and has held concerts by Jamie Cullum, The Kit Downes Trio and other Yamaha-linked artists, often in conjunction with UK charity Centrepoint.