Yao Simon began his professional footballing career in Ivory Coast in 2000 with Bouna-based club, Sabé Sports de Bouna.

He first moved out of Ivory Coast in 2001 to North Africa and more accurately to Tunisia where he signed a one-year contract with Bizerte-based club, CA Bizertin.

In 2003, he moved to Hammam Sousse where he signed a two-year contract with another Tunisian Ligue Professionnelle 1 club, ES Hammam-Sousse.

In 2011, he again moved out of Ivory Coast and this time to the Middle East and more accurately to the United Arab Emirates where he signed a six-month contract with UAE First Division League club, Al-Urooba.

In 2012, he moved back to North Africa and more accurately to Sudan where he signed a one-year contract with capital city, Khartoum-based, Al-Khartoum Al-Watani SC.

In 2013, he moved to Al-Fashir where he signed a two-year contract with Sudan Premier League club, Al-Hilal Al-Fasher ESC.