For most of this section, the road runs directly alongside the Yarra River after it widens past Dights Falls, with a clean view of the bridges and surroundings.

Route 2 briefly takes in the CBD, driving directly past Crown Casino and the Melbourne Aquarium.

The famous West Gate Bridge spans the Yarra at its widest, and gives a panoramic view of the city, the docks, the industrial western suburbs, and Port Phillip Bay.

This is a drive along the inner-western beachfront to the end of the mini-peninsula at Williamstown, finishing the route alongside a scenery of blue skies, yellow sand and marinas - a far cry from the leafy green beginnings of Warrandyte.

When the route was extended from Ivanhoe East to Warrandyte, it was re-signed using the brown five-sided shield in 1989, usually shown in the centre of a small green and white sign bearing the words Yarra Scenic Drive.