The neighbouring districts are Tyoply Stan to the West, Konkovo and Zyuzino to the North, and Chertanovo to the East.

To the South, the area beyond the Ring Road has never been developed; it was part of the Moscow Oblast until 2012 when it was assigned to the newly created Novomoskovsky Administrative Okrug.

As of July 2020, Yasenevo was ranked 55th among Moscow's districts in terms of average housing prices.

[6][7] The highest point of Moscow is located in Yasenevo close to the Tyoply Stan metro station, at 255.2 metres above sea level.

"[9] In the English-speaking world, Yasenevo is known for hosting the headquarters of Russia's Foreign Intelligence Service (SVR).