Yatesboro is an unincorporated community that is located in Cowanshannock Township, Pennsylvania.

The community is situated 1.0 mile (1.6 km) west of Rural Valley.

It was built on farmland by the Rochester and Pittsburgh Coal and Iron Company.

[4] It was one of seventeen company towns that were sold in 1947, including McIntyre, Coal Run, Iselin, Waterman, Lucernemines, Aultman, Ernest, Tidesdale, Coy, Luciusboro, Fulton Run, Nu Mines, Yatesboro, Margaret, Helvetia, Twin Rocks, and Yatesboro Lots.

Yatesboro appears on the Rural Valley U.S. Geological Survey Map.