She has appeared in advertisements for Garnier Fructis, Lincoln Townhouse, Oil of Olay, Radioshack, Seda, Sephora and Dr. Scholl's.

She has graced the covers of numerous magazines, including W,[7] Hype Hair,[8] Splash and Global Modeling.

[10] She then starred opposite Rob Brown, Antonio Banderas and Alfre Woodard in the 2006 dance film Take the Lead.

She appeared in the ABC soap opera All My Children in 2008 as Cassandra Foster, the daughter of Angie Hubbard (Debbi Morgan).

Later, she appeared in the magazines, including on the cover of W (September 2010),[15] in L'Officiel (in November 2010),[16] and in Vogue (in January 2011 by Patrick Demarchelier).

[17] In 2013, she also appeared as Carol in the historical drama film The Butler, starring Forest Whitaker and Oprah Winfrey.

[19] Also from 2015 to 2021, DaCosta starred in the NBC medical drama Chicago Med as April Sexton, an ED nurse.