Born in Istmina in the Chocó Department of Colombia, Mosquera played for Sócrates Valencia in his youth.
[6] Despite this interest, Mosquera remained with Orsomarso, but in August of the same year, he was strongly linked with English Premier League side Aston Villa, with the West Midlands club reportedly making a formal approach.
[7][8] On 30 August 2024, Mosquera signed for English Premier League club Aston Villa for an undisclosed fee, being assigned to their academy.
[11] Mosquera was first involved with the Colombia under-20 side in May 2024, being part of manager César Torres' first squad for a microcycle.
[13] Mosquera was included in Colombia's squad for the 2025 South American U-20 Championship for their games against Bolivia, Brazil, Argentina and Ecuador.