Yellow Jack is a 1934 docudrama play starring James Stewart and produced by Guthrie McClintic that was later adapted into a 1938 Hollywood movie by the same title.

Limited in its experiments by the fact that animals are immune to Yellow Jack and embroiled in government interference, Reed decides that the only way to test the theory is to expose his own men to the disease.

A single performance for members of the U.S. armed services, the abbreviated version of the play featured actors from the simultaneous Broadway production of Winged Victory, also directed by Ritt.

The cast—nearly all of them active-duty military—included John Forsythe (O'Hara), Gary Merrill (Walter Reed), Grant Richards (Aristides Agramonte), Philip Bourneuf (Dr. Carlos Finlay), George Reeves (James Carroll) and Whit Bissell (Brinkerhof).

[8][9] The play was adapted for an episode of the NBC–TV series Producers' Showcase, broadcast January 10, 1955, directed by Delbert Mann and starring Jackie Cooper and Broderick Crawford.