The Yellow Turbans launched an uprising against the central government in 184, the year of the Jiazi in the Sexagenary cycle.
When Zhang Jue saw that followers of the Way of the Taiping grew more numerous by the day, he openly revolted in the large-scale Yellow Turban Rebellion.
The Rebellion was put down within the year, but laid the foundations of the fall of the Eastern Han dynasty.
The central government handed local officials immense authority with regards to the recruitment of soldiers, which resulted in the warlordism of the late Eastern Han dynasty and the Three Kingdoms Era, undeniably a fatal blow to the Eastern Han.
This is also why the Yellow Turban Rebellion is often documented in Chinese historiography as the beginning of the Three Kingdoms Era.