She holds a Bachelor's and master's degrees with distinction in Political science from Taras Shevchenko National University of Kyiv.

Yasko was the first Ukrainian who graduated from Blavatnik School of Government, University of Oxford, holding a master's degree in Public Policy.

She coordinated a number of events, including the music commemorative campaign "Witness", devoted to the 75th Anniversary of the Babi Yar tragedy, which won the first Cannes Lion Award in the history of Ukraine.

She also was the executive officer for the multimedia project "UN Hundred," presented on behalf of Ukrainian delegation to the United Nations at its General Assembly sessions in 2014 and 2015.

She conducted research and produced a policy recommendation on the improvement of access opportunities in arts education for disadvantaged communities in the UK.

[citation needed] Yasko expressed her concerns regarding the preliminary agreement by Ukraine to the Trilateral Contact Group in Minsk proposals on the envisioned Advisory Council.

[13] Yasko has been engaged in drafting legislation on a range of issues, including the regulation of lobbying,[14] countering corruption,[15] equal representation,[16] remedial action in the wake of Russian military aggression in Ukraine.

[21] This resulted in the establishment of the informal inter-parliamentary group Baltic Plus, together with the delegations of Estonia, Latvia, Lithuania and Georgia.

Yasko also noted that the goals for the delegation for the Winter Session 2020 would be the de-occupation of Crimea, countering Russian aggression in eastern Ukraine, liberation of political prisoners, implementation of Minsk agreements, enhancement of the international sanctions, as well as fight against authoritarianism in Russia itself.

[24] On 31 January 2020, the Ukrainian Delegation, together with the representatives of Estonia, Great Britain, Georgia, Iceland, Latvia, Lithuania, Moldova, Slovakia and Sweden, signed the joint declaration expressing regret of the Assembly's approval of the credentials submitted by the Russian Federation.The signatories to the declaration also demanded on Russia's implementation of resolutions adopted in previous years in respect of the armed aggression in Ukraine, Georgia, and of the utmost concern at the treatment of Crimean Tatars.

In March 2020 Yasko, along with colleagues from the Servant of the People Party, opposed the proposed establishment of an Advisory Council within the framework of the Minsk Trilateral Contact Group.

Yasko argued that the Advisory Council's establishment would change the format of the negotiations, turning the Russian Federation into an observer rather than a direct participant in the conflict, that it would carry with it recognition of the representatives of the Donetsk and Luhansk People's Republics, considered by Ukraine as "terrorist organizations", as legitimate representatives of ORDLO (temporarily occupied territories of Ukraine), that it would undermine the Ukrainian position in international courts and the potential for compensation for Ukraine for damages and losses caused by Russia.

According to Yasko, approving the Advisory Council format would risk bringing defeat for Ukraine on international platforms, the lifting of international sanctions imposed on Russia during the course of its armed aggression, and defeat for Ukraine in its efforts to fight for the truth about Russian aggression in the information war.

On 16 March 2019, along with other MPs, Yelyzaveta Yasko signed a letter to the Secretary of the National Security and Defence Council of Ukraine, Oleksiy Danilov, requesting the dismissal of his advisor Serhii Syvokho [uk] in connection with his statements regarding 'internal conflict in Donbas', which ran contrary to Ukrainian law, where the Russian Federation is officially recognised as an aggressor country against Ukraine.

Along with a group of other deputies from 'Servant of the People', Yelyzaveta Yasko publicly supported draft law 3260, on amendments to legislative acts of Ukraine to improve certain mechanisms for regulating banking activities.

In a post on her Facebook page, Yasko stated: 'This bill will make it impossible to repeal the NBU's decision on the nationalisation/liquidation of banks and unfairly compensating their former owners.'

She authored or co-authored bills on granting the status of participant in hostilities to volunteers, on the ethical principles of members of parliament, on the creation of the National Agency of Ukraine for Overcoming the Consequences of Armed Aggression of the Russian Federation, on the transparent regulation of lobbying, on improving the effectiveness of anti-corruption law enforcement, and on equal gender representation.

Yasko was one of the initiators of the bill on the Verkhovna Rada's appeal to the parliaments of other states and parliamentary assemblies of international organisations to condemn Russian armed aggression and human rights violations in occupied Crimea.

[citation needed] Yasko was also a member of the Science Community at Faculty of Philosophy and received numerous diplomas for the best research papers at conferences in politics and international affairs.