The construction of a 6 GeV electron synchrotron accomplished in 1967 became an important landmark in the history of institute, it is the first particle accelerator in Armenia (Arus "ԱՐՈՒՍ").
After collapse of Soviet Union YerPhI continued research in the fields of high-energy physics and astrophysics in Armenia and worldwide using world biggest accelerators and cosmic ray detectors.
During 1970-1991 synchrotron was operated with energies up to 4,5 GeV and in Experimental Physics Division were obtained significant results, including: hadronic properties of photons in π- meson photo-production on nuclei; structures of nucleon resonances in multi-polarization experiments, structure and characteristics of nuclear matter, important properties of X-ray transition radiation and channeling in monocrystals.
Wide spark chambers and transition radiation detectors are examples of the experimental techniques developed and implemented in YerPhI.
During the last years groups of scientists from Yerevan Physics Institute have actively participated in intermediate and high energy physics experiments abroad (JLAB, DESY, CERN-LHC, MAX-lab, MAMI), exploring the meson and nucleon structures, electromagnetic interactions of the nucleon, quark-hadron duality, short range nucleon-nucleon correlations, quark hadronization in nuclear medium, physics beyond standard model, Higgs boson searches, quark-gluon plasma, fission and fragmentation of nuclei and hypernuclei and many other topics, as well as constructing experimental hardware and develop the software for data acquisition and analysis.
In the mid-1980s in YerPhI was developed the concept of stereoscopic approach in Very High Energy gamma-ray astronomy using multiple Imaging Atmospheric Cherenkov Telescopes (IACT).
In the course of many years, the Applied Physics Department of YerPhI successfully investigates electron-energy structure of new wide-band laser materials using synchrotron radiation in various spectral regions.