He has won Ananda Vikatan Cinema Award for Aandavan Kattalai (2016), Kolamavu Kokila (2018), Pariyerum Perumal (2018), Love Today (2022) and Maaveeran (2023).

In 2013, he appeared in his first extended comedy role with Pattathu Yaanai (2013)[16] while he also featured in the Hindi film, Chennai Express alongside Shah Rukh Khan.

[18] Yogi Babu had a breakthrough year in 2016, featuring in 20 films, and winning critical acclaim for his role alongside Vijay Sethupathi in Aandavan Kattalai (2016).

[19] This was followed by his role in Kolamavu Kokila (2018) where his one-sided lover portrayal opposite Nayanthara was critically acclaimed[20] while the Kalyana Vayasu song[21] and his antics in it went viral.

[26] He later played in leading roles as Pei Mama (2021), Panni Kutty (2022), Bommai Nayagi (2023), Yaanai Mugathaan (2023), Lucky Man (2023), Thookudurai (2024) and Boomer Uncle (2024).