Yoon has since moved on to acting and is best known for starring in the television dramas Princess Hours (2006), The Vineyard Man (2006), Coffee Prince (2007), My Fair Lady (2009), Lie to Me (2011), and Missing You (2012).

Initially, fans of the Goong manhwa questioned her acting ability, and sent out petitions against Yoon as the lead role, requesting her to be replaced.

[12] The Vineyard Man initially suffered low ratings, but received positive reviews for its heart-warming storyline and the cast's performances, and eventually rose in viewership.

[10] In 2009, Yoon starred in KBS' romantic comedy My Fair Lady, playing an arrogant, strong-headed heiress of a rich business family.

[18] Although My Fair Lady was a moderate success, Yoon was harshly criticized for her unnatural speech and accent as well as her regression in acting skills.

[19][20] Yoon returned to the big screen after five years with the coming-of-age film My Black Mini Dress (2010), based on the same titled chick lit novel by Kim Min-seo.

[21] She then starred in SBS's romantic comedy series Lie to Me (2011), playing a smart government official who is unlucky in the love department.

[23] In 2012, Yoon made her directorial debut with the short film The Knitting, which was her first assignment as a graduate student at Chung-Ang University.

[30][31] This was followed up with a leading role in KBS's romantic comedy Marry Him If You Dare, where she played a 32-year-old call center agent who travels back in time to change her future.

[36] In 2017, Yoon made her return to the Korean entertainment industry by appearing as a regular in tvN's variety show Dear Pet, We Need to Talk.

Eight Peaks claimed that they had no knowledge of this so-called incident and spread a rumour of Yoon's irresponsibility online which damaged her reputation.

These actions included the improper handling and distribution/division of earnings and proceeds as well as the unilateral (one-sided) manner of making and carrying out decisions which caused immense problems.