Yoshihiro Kikuhime (吉弘菊姫, d. November 4, 1595) was a Japanese noble woman member of the Ōtomo clan from the late Sengoku period.

However, in 1593, following the disgrace of her husband, Yoshimune, who had faltered as a military commander during the Invasion of Korea, she was expelled from Osaka.

Denied the opportunity to accompany her husband into exile, she faced a tragic destiny, wandering through Bungo Province with her three young children, lacking any form of support.

She sought refuge with her nephew, Tachibana Muneshige, who was the lord of Yanagawa Castle, and was given a residence in Zen'in Village in Chikugo Province.

Despite the prohibition of Christianity at the time, she was buried according to Nichiren Buddhism customs, and her posthumous Buddhist name was "Sonjuin Den Nissho Daijo."