Yoshito Sengoku (仙谷 由人, Sengoku Yoshito, born January 15, 1946 – October 11, 2018) was a Japanese politician serving in the House of Representatives in the Diet (national legislature) as a member of the Democratic Party of Japan.

Viewed as a close ally of Prime Minister Naoto Kan, the opposition Liberal Democratic Party has labeled Sengoku as the "second" Prime Minister of the Kan cabinet.

Sengoku denies that he wields any extraordinary influence in the government and praised Kan as a "strong leader".

[1] In January 2011, he was ousted from his position as a top cabinet member due to swelling pressure from the opposition, namely the Liberal Democratic Party and Komeito Party, to execute cabinet reform.

In March 2011, Prime Minister Naoto Kan appointed Sengoku as Deputy Chief Cabinet Secretary.