[13] On 24 March 2010, Younis, along with teammate Mohammad Yousuf, was suspended from playing by the Pakistan Cricket Board following an inquiry report which suggested they were involved in breaches of discipline by inciting divisions within the team.
Younis was batting in the second ODI against West Indies in Faisalabad when the news of his brother's death reached the team management.
Younis also mentioned his grief at the death of Bob Woolmer in March 2007 after Pakistan's exit from the World Cup.
[24] During a tour of the West Indies in May 2011, Younis was given permission to return home early due to the death of his elder brother Shamshad Khan in Germany.
In doing so he was the third overseas Asian cricketer to play for Yorkshire following Sachin Tendulkar and Yuvraj Singh, and was succeeded by Pakistani player Inzamam-ul-Haq.
[27] However, on his one-day debut in the Friends Provident Trophy, Younis hit a superb 100 from 92 balls against Nottinghamshire to lead Yorkshire to victory.
Younis also made a useful contribution bowling during Hampshire's second innings, picking up four wickets for just 52 runs, however despite his and the team's efforts the match ended in a draw.
[34] Younis was one of the few batsmen who retained his place in the team after Pakistan's disastrous World Cup campaign in 2003, but lost it soon after due to a string of poor scores in the home series against Bangladesh and South Africa.
It was his return to the side in October 2004, at the pivotal one-down position, against Sri Lanka in Karachi that laid the groundwork for his emergence as a force in Pakistan cricket.
Once, Craig McMillan hit Younis for 26 runs, 4 4 4 4 6 4 in an over, a then world record, during the 3rd Test at Westpac Trust Park, Hamilton.
[41] More importantly, the tour to India also showcased his potential as a future captain of Pakistan and his energetic and astute leadership impressed many people.
[42] On 22 January 2007, he scored a matchwinning unbeaten 67 in the 4th innings to guide Pakistan to victory over South Africa in Port Elizabeth.
[46] Younis ranking score of 880 is the third highest achieved by a Pakistani batsmen after Mohammad Yousuf (933), Javed Miandad (885) and just ahead of Inzamam-ul-Haq (870).
[48] He first led Pakistan Test team against the same West Indies tour in 2005, where regular captain Inzamam was given one-Test ban for showing dissent against India.
Following the resignation of Inzamam after the Pakistan's exit from the 2007 Cricket World Cup, Khan was offered the captaincy on a permanent basis, but he turned it down.
[52] Younis led his team to the ICC World Twenty20 title for the first time by beating Sri Lanka at Lord's.
After Pakistan's 2–1 defeat to Sri Lanka in 2009, PCB chairman Ijaz Butt appointed Younis Khan as the permanent captain of both the Test and ODI teams.
[54] Khan resigned as captain on 13 October 2009 due to a parliamentary investigation into match fixing that was alleged to have taken place during his reign.
Pakistan Cricket Board announced that Younis Khan had been banned indefinitely for "infighting which brought down the whole team during the tour of Australia in January".
Despite being the first-choice for captaincy, the selecting panel Mohsin Khan announced that Misbah-ul-Haq was recalled and made captain.
[66] On 31 August 2010, the Daily Telegraph in its news article mentioned that Younis Khan was associated with alleged match-fixer Mazhar Majeed.
[67] The Pakistan Cricket Board subsequently announced that they had successfully reconciled with Younis and that they intended to use him on the tour of South Africa in October 2010 as a replacement for the injured Mohammad Yousuf.
His performance was praised as he came in to bat at a very difficult time with the score being just 19/2 and played a major role in helping Pakistan post a commanding total.
[89] Pakistan successfully chased a total of 377 runs in fourth innings against Sri Lanka in the third Test match.
One of his main weaknesses is playing away from the body, he also has a tendency to leave straight balls, a trait that has been exploited by bowlers in the past, particularly by the Australian attack.
Along with Mohammad Yousuf and the now retired Inzamam-ul-Haq, he formed a formidable middle order batting line up for Pakistan.
[98] On 11 November 2015, Younis announced his retirement from ODI format saying that the opening match of the Pakistan against England will be his last one.
However, in a conversation in Karachi, Younis opened his idea about the retirement, where he can extend his international career, but only if the Pakistan board and team needs him to do so.
One of the sticking points had to do with finances, while the other was with the job profile, as the PCB had proposed Younis only be a mentor and a coach but he wanted a say in selection as well.
"[126] On 2 April 2022, Younis Khan was named as the batting consultant of Afghanistan on a temporary contract for a training camp which lasted 15 days in the UAE.