Yupukari (also: Eupukari[2]) is an indigenous village of Macushi and Wapishana Amerindians in the Upper Takutu-Upper Essequibo Region of Guyana.

[4] The economy is based on subsistence farming, hunting, fishing and tourism.

[3] The Caiman House Eco Lodge is located in the village.

[6] Yupukari is known for the great variety of butterflies who visit the region.

[7] The Yupukari Wildlife Club has constructed a community butterfly farm in the village.