After gold, silver and other precious metals were found in its foothills in 1746, Spanish mining companies flooded the area and Spaniards settled the town.

Years of exploitation by the Spanish and later by North American mining companies followed, bringing both advantages and disadvantages.

At its height, Yuscarán was a wealthy mining town and home to some of Honduras's most influential families.

However, after the mining stopped, most of the foreigners supporting Yuscarán abandoned the town, taking their money and possessions with them.

The Yuscarán factory, also called the Distileria del Buen Gusto, was founded in 1939.