Her main subjects were landscapes and seascapes celebrating the Suffolk countryside, along with still life pictures of flowers, plants and trees, including those growing in her own garden; she also produced occasional portraits.

She is mentioned in Patrick Trevor-Roper's influential book The World Through Blunted Sight: An inquiry into the influence of defective vision on art and character (1970) as having different colour perception in each eye.

[7] Her works are rarely titled, and whilst the landscapes are clearly recognisable, they are not usually particularly well-known views, although she did paint Snape Maltings and Shingle Street.

She generally worked from life and travelled around Suffolk and Norfolk in a Fiat 238 camper van seeking suitable subjects.

In 1943 Yvonne Drewry illustrated "World Under Water, the Adventures of Matthew, Jill and Poco", published with Robert Campbell at the Symbole Press, Woodford Green, Essex.

Drewry produced her own exhibition catalogues and posters in letterpress, and also created her own Christmas cards, which were usually multi-coloured linocuts, showing the influence of Joan Hassall.

Drewry was an important teacher of art at the Amberfield School in Nacton,[11] in Felixstowe, and at various local authority run evening classes for adults; she also ran short painting and printing courses in her own home.

[12] Her pupils included Maggi Hambling, who cites her as a major childhood influence,[13][14][15] and Malta based artist Juliet Horncastle.