Yzeures-sur-Creuse (French pronunciation: [izœʁ syʁ kʁøz], literally Yzeures on Creuse) is a commune in the department of Indre-et-Loire, Centre-Val de Loire, France.

It is one of the oldest towns in Touraine, occupation dating back to the Upper Paleolithic era earlier than 10,0 CE.

The Creuse meets its tributary Gartempe 3 kilometres (1.9 mi) from Yzeures near the spa town of La Roche-Posay.

Yzeures sur Creuse lies at the meeting point of the three departments of Indre-et-Loire (37), Indre (36) and Vienne (86).

You can see pictures, posters and audio-visual materials, and also her stage costumes presented in reconstituted sets of her greatest roles.