Zacarías Colque Matías (8 February 1967 – 24 September 2022) was a Bolivian agricultural worker, politician, and trade unionist who served as a member of the Chamber of Deputies from Potosí, representing circumscription 38 from 2015 to 2020.

[4] An ethnic Quechua,[5] Colque spent his early life in rural poverty, making a living as an agricultural worker before becoming active in the regional's peasant labor movement.

These positions opened the door to more prominent roles, and he topped off his union career as executive secretary of the Unified Syndical Federation of Native Workers of Northern Potosí.

[6] In office, Colque focused his parliamentary term on indigenous matters, supporting projects to recognize and promote native culture[9] and occupying positions on committees related to the topic.

[10] As with the vast majority of legislators who entered parliament in representation of MAS-aligned groups, Colque was not nominated for reelection, reflecting the party's practice of renewing its electoral lists to make way for new leaders from allied social sectors.