He played in Major League Baseball (MLB) for the Chicago White Sox, Toronto Blue Jays, Pittsburgh Pirates, and Cleveland Guardians.

[8] After signing, he made his professional debut with the Arizona League White Sox and was promoted to the Winston-Salem Dash after three games.

After the season, the White Sox assigned Collins to the Glendale Desert Dogs of the Arizona Fall League (AFL).

[11] He spent 2017 with both Winston-Salem and the Birmingham Barons, posting a combined .224 batting average with 19 home runs and 53 RBIs in 113 games in total between the two clubs.

[16] On April 14, 2021, Collins caught the 20th no-hitter in White Sox history, which Carlos Rodón pitched.

On September 6, 2022, Collins was claimed off waivers by the Pittsburgh Pirates and was optioned to the Triple-A Indianapolis Indians.

[22] On August 17, Collins was selected to the 40-man roster and promoted to the major leagues to replace catcher Cam Gallagher, who had been placed on the injured list with a concussion.