[4][5] He was born to the Makdoom family in the early months of Hijra 938 (c. 1531 CE) at Chombala (Azhiyoor Panchayath, Calicut District, Kerala State, India) Near Mahe, and received religious instruction under the supervision of his grandfather.
He completed his primary education under his father Muhammed Gazzali and his uncle Abdul Azeez Bin Sheikh Makhdoom Al Avval ( عبد العزيز بن شيخ مخدوم الآول) and left for Makah for further study.
After the decade-long stay in Makkah, he returned to Kerala and took charge as chief Mufti in the grand Masjid of Ponnani, a position he occupied for thirty-six years.
In his masterpiece Tufathul Mujahideen Fi Akhbar ul Burthugalin, he narrated the brutality of the Portuguese on the Malabar soil with special reference to their anti-Muslim stance.
In the aforementioned text, he motivated them by exuding the endless promises of the Almighty for those who waged war against them, and boosted their morale by leading their mind to the sweet memories of the golden age of Islam.