In a press conference following UFC 98, Dana White announced that filming for the season would begin on June 1, 2009.

All competitors invited to Las Vegas for the show's taping participated in the entire season.

A previously announced bout between Rousimar Palhares and Lucio Linhares was moved to UFC 107.

[10] Linhares was a replacement for Alessio Sakara who had to pull out due to rumored visa issues.

[13] Matt Veach, who was previously scheduled to fight Mark Bocek on the event's undercard was named as Edgar' new opponent.