The original institution was founded by the Zamorin of Eranad, HH Shri.

In 1878, it came to be known as "Kerala Vidyasala" and was thrown open to Hindu boys of all castes.

The present site of the college at Pokkunnu was purchased with the help of a grant from the Guruvayur Devaswom.

PhD is offered in Botany, Economics, Malayalam, Chemistry and English.

[1] Zamorins Guruvayurappan college is one of the oldest institution in the country celebrating its 144th anniversary in 2021.