The upper reaches in Yunnan and Guizhou were once known as the Zangke River.

The Beipan River passes through the modern Chinese provinces of Yunnan and Guizhou.

The river was significant in history as a communications pathway between the Yelang and Nanyue kingdoms.

[1] The river is crossed by the Duge Bridge, the world's highest, the Qinglong Railway Bridge, the Guanxing Highway via the Beipan River Guanxing Highway Bridge, the Liupanshui-Baiguo Railway via the Beipan River Shuibai Railway Bridge, and the G60 Hukun Expressway via the Beipan River Hukun Expressway Bridge.

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