Zaniolepis, the combfishes, is a genus of marine ray-finned fish, it is one of two genera in the family Zaniolepididae.

Z. frenata that was a source of food to the Native American inhabitants of San Nicolas Island off the coast of southern California, United States during the Middle Holocene.

[5] Zaniolepis was first proposed as a monospecific genus in 1858 by the French zoologist Charles Frédéric Girard when he described Z. longispinis from Fort Steilacoom on Puget Sound in Washington.

[8] The currently recognized species in this genus are:[9] Zaniolepis combfishes have a deep incision in the rear third their dorsal fin and the first 3 spines in the dorsal fin are highly elongated, extremely so in Z. latipinnis.

[9] Zaniolepis combfishes are found in the eastern North Pacific Ocean from Alaska to Baja California.