[3] In July 2003, Grygera was signed by Dutch club Ajax for an undisclosed fee, estimated to be around €3.5 million.

[8][9] He received the number 26 jersey and made his Fulham debut on 15 September 2011 in the UEFA Europa League against Twente.

[10] Grygera suffered an anterior cruciate ligament rupture during a league match against Tottenham Hotspur on 6 November 2011, which kept him out for the rest of the season.

"[12] On 6 December 2012, Jol confirmed that Grygera had decided to retire from football to concentrate instead on returning to full fitness.

[15] At the 2006 FIFA World Cup, Grygera's run and cross set up the opening goal for Jan Koller in the Czechs' first match against the United States, which they 3–0.