[1] Myrie was born in Brooklyn, New York City to Costa Rican-born immigrant parents and raised in the Prospect Lefferts Gardens neighborhood.

[2] He graduated from Brooklyn Technical High School and attended Fordham University, earning his undergraduate and Master's degrees in urban studies.

[5][6] Before law school, Myrie worked for the New York City Council as a legislative director where he helped draft the Tenant Bill of Rights.

As an associate at the firm, Myrie worked more than 600 pro bono hours in one year.

[17][18] On May 30, 2020, Myrie was pepper-sprayed and handcuffed while taking part in protests following the murder of George Floyd.

[21] Myrie supports financial institutions having the right to deny lending capital to ammunition and gun industries.