Zhengzhou–Wanzhou high-speed railway (Chinese: 郑万高速铁路) is a high-speed railway connecting Zhengzhou, the capital of Henan province, and Wanzhou District in Chongqing.

The section from Xingshan to Wanzhou also forms part of the Shanghai–Chongqing–Chengdu high-speed railway.

The railway was approved by the National Development and Reform Commission in 2014.

[3] Construction began in 2016, and the line fully opened in June 2022.

[4] The remaining section between Xiangyang and Wanzhou opened on 20 June 2022.