Zhizdrinsky District (Russian: Жиздринский райо́н) is an administrative[1] and municipal[4] district (raion), one of the twenty-four in Kaluga Oblast, Russia.

It is located in the south of the oblast.

The area of the district is 1,250 square kilometers (480 sq mi).

[2] Its administrative center is the town of Zhizdra.

[8] The population of Zhizdra accounts for 55.0% of the district's total population.