Zhou Bo (died 169 BC), posthumously known as Marquis Wu of Jiang (绛武侯), was a Chinese military general and politician who served as a chancellor of the early Western Han dynasty.
After Liu Bang became emperor and established the Han dynasty, he enfeoffed Zhou Bo as the Marquis of Jiang (絳侯) to honour him for his contributions in battle.
During the regency of Empress Lü, Zhou Bo served as Grand Commandant (太尉).
Zhou Bo later served as the Right Chancellor during the reign of Liu Bang's son, Liu Heng (Emperor Wen), but resigned within a year as he realised that his aptitude for the position was inferior to that of Chen Ping's.
One of Zhou Bo's sons, Zhou Yafu, served under Liu Qi (Emperor Jing), Emperor Wen's successor, and played a key role in suppressing the Rebellion of the Seven States.