Zhou Xin (died 196) was a Chinese politician who lived during the late Eastern Han dynasty of China.
After he grew up, he entered government service and was appointed as the Administrator (太守) of Danyang Commandery (丹陽郡; around present-day Nanjing, Jiangsu).
Later, Yuan Shu sent Wu Jing to lead troops to attack Zhou Xin.
In 196, Zhou Xin came into conflict with the warlord Sun Ce, who was on a series of conquests in the Jiangdong region, where Kuaiji Commandery was.
Wang Lang, the Administrator of Kuaiji Commandery, ordered Zhou Xin to lead troops to attack Sun Ce.