Zhu Gui first appears in the novel when Lin Chong comes to join Liangshan on the recommendation of the nobleman Chai Jin after killing three men sent to murder him by the Grand Marshal Gao Qiu.

Zhu introduces himself to Lin Chong and leads him through the marsh to the stronghold to meet Wang Lun and the other two chiefs Du Qian and Song Wan.

Wang Lun tries to send Lin Chong away with gifts and excuses for fear that the latter, a reputedly good fighter, would usurp his place.

Chao Gai and his six robber partners seek refuge in Liangshan after they are found to be the hijackers of the valuables in transportation to Grand Tutor Cai Jing.

When Li Kui goes back to his home in Yishui to fetch his mother to Liangshan, Song Jiang is worried that he would get into trouble with his quick temper.

As Zhu Fu has learnt martial arts from Li Yun, the latter, together with his men, unsuspectingly drinks the spiked wine that he offers.

Zhu Gui is put in charge of an inn which acts as a lookout for Liangshan after the 108 Stars of Destiny came together in what is called the Grand Assembly.