On the south-western part of the region, there are the Chřiby highlands with the highest point Brdo (587 m).

Most of the soils in the region are poor in minerals (with the exception of potassium and magnesium) and humus.

It is rather difficult to cultivate soil in a large part of the Region due to the steep land and variety of the terrain.

Average age was 43.1 years, along with Hradec Králové Region the highest in the Czech Republic.

[6] The table shows cities and towns in the region with the largest population (as of January 1, 2024):[7] Other significant towns in Zlín Region are Napajedla, Hulín, Staré Město and Slavičín.

Industrial potential of the region lies in manufacturing enterprises that represent 16% of total registered entities.

As of end 2012, the Zlín Region had 138,269 legal and physical entities out of which 14,379 had employees.

[10] The length of operated railway lines in the region is 359 km (223 mi).

Acute, successive and rehabilitation health care is ensured by a network of 10 hospitals with 2,849 available beds.

[3] The Zlín Region is attractive for tourists and boasts a number of natural, cultural and historic landmarks such mountains, garden architecture, spas, wine valleys, remains of the Great Moravian empire, series of religious monuments and historically valuable buildings as well as a unique example of modern Baťa's functional architecture.

Most agricultural soil belongs to the Uherské Hradiště District (57 277 Hectares, of which 70.1% is arable land).