It stars RKO's imitation Abbott and Costello, Alan Carney and Wally Brown, as a pair of men who are tasked with finding a real zombie for a zombie-themed nightclub.

They discover a lead from a museum curator that a mysterious Professor Renault lives on the Caribbean island of San Sebastian and has been creating zombies.

Followed by Ace's henchmen, the boys are immediately placed on a tramp steamer sailing to San Sebastian in the Virgin Islands and ordered to bring a real zombie back or forfeit their lives.

[2] Zombies on Broadway turned in a profit for RKO, which encouraged the studio to re-unite Brown, Carney, Anne Jeffreys and Bela Lugosi for the film Genius at Work in 1946.

"[4] Writing in The Zombie Movie Encyclopedia, academic Peter Dendle said, "Brown and Carney aren't funny, and it's sad to see Lugosi outwitted by a pack of morons.