The County of Zweibrücken-Bitsch (German: Grafschaft Zweibrücken-Bitsch, French: comté de Deux-Ponts-Bitche) was a territory of the Holy Roman Empire that was created between 1286 and 1302 from the eastern part of the County of Zweibrücken and the Barony of Bitche (German: Bitsch) in Lorraine.

Other lands were initially managed jointly by Eberhard I and his younger brother, Walram I, who had been given the Amt of Zweibrücken.

In the 16th century, Count James succeeded for the last time in establishing a clear concentration of power in northern Alsace and the southern Palatinate.

However, since James and his brother Simon V Wecker (died 1540) had each only produced a daughter, a dispute broke out in 1570 after James' death between the husbands of the two cousins, Count Philip I of Leiningen-Westerburg and Count Philip V of Hanau-Lichtenberg.

[1] During the subsequent trial before the Reichskammergericht, Lorraine was able to point both to the exchange agreement of 1302 as well as the fact that, in 1573, it had purchased the hereditary rights of the counts of Leiningen.