Zygmunt Karol Radziwiłł (Lithuanian: Zigmuntas Karolis Radvila; 1591-1642[1]) was a Polish-Lithuanian noble, who served as the Chamberlain (podkomorzy) at Poznań from 1625, Queen's Carver (krajczy) from 1617, Carver of Lithuania from 1633, Cupbearer of Lithuania from 1638, and Governor (voivode) of Nowogródek from 1642.

Radziwiłł was born on 4 December 1591 in Nieśwież[2] to Mikołaj Krzysztof "Sierotka" Radziwiłł (nicknamed "The Orphan") and Halaszka Eufemia Wiśniowiecka, and died on 5 November 1642 in Assisi, Italy.

In 1621, he took part in the Battle of Khotyn (1621),{{cn|date=November 2024]} and later commanded Lisowczycy mercenaries in 1622 during the period of their service in the Holy Roman Empire.

[3] After the death of his older brother, Albrycht Władysław Radziwiłł, he inherited ordynacja of Nieśwież in 1636, but gave it up to his brother Aleksander Ludwik Radziwiłł.

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