Mislan learned from his father how to play the clarinet and the euphonium (the latter is essential in the performance of Puerto Rican danzas).
His style differed from that of Manuel Gregorio Tavárez and Juan Morel Campos in that his danzas were typically shorter and humorous.
Besides writing danzas, Mislan also wrote Puerto Rican folk music, waltzes and marches.
Most of his works are safeguarded in the Instituto de Cultura Puertorriqueña (Institute of Puerto Rican Culture).
The City of San Sebastián honored Mislan's memory by naming a school after him and by placing a bust of his image in the center of its plaza.