Trains of the Nara Line depart from and arrive at the station.

Ōsaka Namba Station is served by the following two lines.

The station has an island platform and a side platform with three tracks on the third basement level, parallel to Namba Station on the Osaka Metro Sennichimae Line.

The station was first named Kintetsu Namba Station (近鉄難波駅, Kintetsu-Nanba-eki) on March 15, 1970, when Kintetsu's Namba Line opened.

[1] It was renamed to the present name on March 20, 2009, the date of opening of the Hanshin Namba Line.